Silo Meoto earns Enterprise Fellowship

Silo-Aerograft2Dr Silo Meoto has been awarded a prestigious Enterprise Fellowship to support her in developing a novel bone graft substitute (AeroGraft) into a commercial product.

 

The Royal Academy of Engineering's Enterprise Hub has identified eight of the most promising new technologies developed at UK universities with the potential to make a major social and economic impact. The Enterprise Hub will support the researchers behind these technologies to spin-out their ideas into successful businesses.

 

The Enterprise Fellowships provide mentoring from Academy Fellows, who include some of the UK's top engineering entrepreneurs such as Sir Robin Saxby FREng, former chief executive of British technology giant ARM, and Professor Neville Jackson FREng, CTO of global UK engineering company Ricardo. Each entrepreneur will also receive bespoke training and up to £60,000 of funding through the Academy's Enterprise Hub to spend the next 12 months exclusively developing a business based on their innovations.

 

During her PhD, Silo worked on the synthesis and characterization of a nanoporous silica composite membrane. Her experience extends to the characterization and testing of other hierarchically structured materials for different applications, such as the AeroGraft material of the RAE Enterprise Fellowship project. AeroGraft has been developed as a material that could transform dentistry, enabling new bone graft substitutes to integrate into chipped or damaged teeth and potentially achieve 95% integration with the surrounding bone in just 3 months. The technology could dramatically reduce the time and cost of repairing tooth fractures and allow people who have lost a large amount of bone to receive implants. It has already undergone in-vitro studies in partnership with dentists and could eventually be used to aid tooth replacement. The RAE Enteprise Fellowship award will serve to bring this product closer to market.

 


She will use ARCHER supercomputer for 6 months to study behavior of biomolecules confined in ordered amorphous silica through all-atom molecular dynamic simulations with explicit water and counter-ions.The simulations will provide a better understanding of the interplay between the adsorbed proteins and mesoporous materials which is necessary to improve drug delivery systems by improving stability and controlled release of the active drug at the site of interest.